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Updated: Jun 8, 2023

Aligos Therapeutics Inc. is a biotechnology company that focuses on developing innovative therapies to treat a range of viral diseases. The company was founded in 2018 and is headquartered in South San Francisco, California. Since its inception, Aligos has made significant strides in the development of novel treatments for hepatitis B virus (HBV) and respiratory syncytial virus (RSV) infections.

One of the main areas of focus for Aligos is the development of therapies for HBV. This is a chronic viral infection that affects millions of people worldwide and can lead to liver failure, liver cancer, and death. Currently, there are no cures for HBV, and the available treatments only suppress the virus rather than eliminate it completely.

Aligos has developed a novel approach to treating HBV, which involves targeting multiple aspects of the virus's life cycle. The company's lead drug candidate, ALG-010133, is a small molecule inhibitor that targets the viral capsid protein, a key component of the HBV life cycle. In preclinical studies, ALG-010133 has shown promising results in reducing viral load and suppressing the virus's replication.

In addition to its work on HBV, Aligos is also developing therapies for RSV, a common respiratory virus that can cause severe illness in infants, young children, and older adults. The company's lead drug candidate for RSV, ALG-1001, is a small molecule inhibitor that targets the viral fusion protein, which is essential for the virus to enter and infect host cells. In preclinical studies, ALG-1001 has shown potent antiviral activity against multiple strains of RSV.

Aligos has also established partnerships with several leading pharmaceutical companies, including Merck and AbbVie, to advance its drug development programs. These collaborations provide Aligos with access to additional resources and expertise to accelerate the development of its therapies.

Aligos Therapeutics Inc. is a promising biotechnology company that is making significant strides in the development of innovative therapies for viral diseases. With its focus on HBV and RSV, Aligos has the potential to make a significant impact on the lives of millions of people worldwide who are affected by these diseases. As the company continues to advance its drug development programs, it will undoubtedly attract the attention of investors and stakeholders looking to support the development of new therapies for unmet medical needs.


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