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Updated: Jun 3, 2023

Adaptimmune Therapeutics PLC is a clinical-stage biotechnology company that specializes in the development of T-cell therapies to treat cancer. The company is headquartered in Oxfordshire, UK, and has operations in the United States.

Adaptimmune Therapeutics is focused on developing next-generation T-cell therapies that are designed to target and destroy cancer cells. The company's proprietary technology platform, called SPEAR (Specific Peptide Enhanced Affinity Receptor), is designed to enable T-cells to recognize and attack cancer cells with greater specificity and potency than traditional immunotherapies.

Adaptimmune Therapeutics has a number of ongoing clinical trials for its lead product candidates, which target various types of cancer, including melanoma, sarcoma, and lung cancer. The company has also formed partnerships with several leading pharmaceutical companies, including GSK and Astellas, to help accelerate the development of its T-cell therapies.

One of Adaptimmune Therapeutics' most promising product candidates is ADP-A2M4, which is being developed for the treatment of synovial sarcoma and myxoid/round cell liposarcoma. In a recent clinical trial, ADP-A2M4 demonstrated a promising safety profile and meaningful clinical activity in patients with advanced synovial sarcoma.

Adaptimmune Therapeutics has a strong financial position, with a cash balance of over $250 million as of December 31, 2021. This provides the company with the resources to continue advancing its product candidates through clinical development and towards commercialization.

Adaptimmune Therapeutics is a clinical-stage biotechnology company that is developing T-cell therapies to treat cancer. With a focus on next-generation immunotherapies and a strong pipeline of product candidates, the company is well-positioned to address significant unmet medical needs in the field of oncology. As the company continues to advance its product candidates through clinical development, investors will be closely watching its progress and the potential impact on cancer treatment.

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